Aging, Sex, and DNA Repair by Carol Bernstein, Harris Bernstein

By Carol Bernstein, Harris Bernstein

Why organisms age and why sexual replica exists are significant unsolved difficulties in biology. This publication offers an built-in rationalization of getting older and intercourse in response to present wisdom of DNA harm and service. Key positive aspects* Discusses the universality of the matter of DNA harm* Describes getting older by reason of collected DNA harm* Considers meiosis as an version for DNA fix* Discusses mating in Read more...

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Cox, B. , and Game, J. C. (1974). Repair systems in Saccharomyces. Mutat. Res. 26, 257-264. , Griffiths, T. , and Carpenter, J. G. (1980). Inhibition and recovery of DNA synthesis in UV-irradiated Chinese hamster V-79 cells. Photochem. Photohiol. 32, 157-165. Friedberg, E. C. (1985). " W. H. Freeman and Company, New York. , and Sauerbier, W. (1976). A radiobiological analysis of the transcription units for heterogeneous nuclear RNA in cultured murine cells. Cell 9, 775-783. References ! 35 Hackett, P.

D N A damage was determined as D N A alterations that give rise to complete molecular b r e a k s during the treatment of purified D N A solutions with single-strand-specific nucleases. T h e D N A was derived from samples of h u m a n muscle of individuals, most of w h o m w e r e undergoing surgical treatment. T h r e e different d e o x y r i b o n u c l e a s e s were used: Si e n d o n u c l e a s e , nuclease Bal 3 1 , and p e a e n d o n u c l e a s e . E a c h nuclease gave similar results.

Int. J. Radiât. Biol. 16, 277-285. Cleaver, J. , Kaufman, W. , Kapp, L. , and Park, S. D. (1983). Replicon size and excision repair as factors in the inhibition and recovery of DNA synthesis from ultraviolet damage. Biochim. Biophys. Acta 739, 207215. Cox, B. , and Game, J. C. (1974). Repair systems in Saccharomyces. Mutat. Res. 26, 257-264. , Griffiths, T. , and Carpenter, J. G. (1980). Inhibition and recovery of DNA synthesis in UV-irradiated Chinese hamster V-79 cells. Photochem. Photohiol. 32, 157-165.

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