By Carol Bernstein, Harris Bernstein
Why organisms age and why sexual replica exists are significant unsolved difficulties in biology. This publication offers an built-in rationalization of getting older and intercourse in response to present wisdom of DNA harm and service. Key positive aspects* Discusses the universality of the matter of DNA harm* Describes getting older by reason of collected DNA harm* Considers meiosis as an version for DNA fix* Discusses mating in eukaryotes as an variation for protecting mutation. Read more...
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Additional info for Aging, Sex, and DNA Repair
Cox, B. , and Game, J. C. (1974). Repair systems in Saccharomyces. Mutat. Res. 26, 257-264. , Griffiths, T. , and Carpenter, J. G. (1980). Inhibition and recovery of DNA synthesis in UV-irradiated Chinese hamster V-79 cells. Photochem. Photohiol. 32, 157-165. Friedberg, E. C. (1985). " W. H. Freeman and Company, New York. , and Sauerbier, W. (1976). A radiobiological analysis of the transcription units for heterogeneous nuclear RNA in cultured murine cells. Cell 9, 775-783. References ! 35 Hackett, P.
D N A damage was determined as D N A alterations that give rise to complete molecular b r e a k s during the treatment of purified D N A solutions with single-strand-specific nucleases. T h e D N A was derived from samples of h u m a n muscle of individuals, most of w h o m w e r e undergoing surgical treatment. T h r e e different d e o x y r i b o n u c l e a s e s were used: Si e n d o n u c l e a s e , nuclease Bal 3 1 , and p e a e n d o n u c l e a s e . E a c h nuclease gave similar results.
Int. J. Radiât. Biol. 16, 277-285. Cleaver, J. , Kaufman, W. , Kapp, L. , and Park, S. D. (1983). Replicon size and excision repair as factors in the inhibition and recovery of DNA synthesis from ultraviolet damage. Biochim. Biophys. Acta 739, 207215. Cox, B. , and Game, J. C. (1974). Repair systems in Saccharomyces. Mutat. Res. 26, 257-264. , Griffiths, T. , and Carpenter, J. G. (1980). Inhibition and recovery of DNA synthesis in UV-irradiated Chinese hamster V-79 cells. Photochem. Photohiol. 32, 157-165.